Actress Christina Applegate is currently hospitalized in Los Angeles, according to a report from TMZ.
Sources with direct knowledge claim the Dead To Me actress was admitted in late March. Applegate’s rep did not confirm or deny if she is in the hospital.
“I have no comment on whether she is in the hospital or what her medical treatments are,” the rep said in a statement to TMZ. “She’s had a long history of complicated medical conditions that she has been refreshingly open about, as evidenced in her memoir and on her podcast.”
Applegate has been open about her struggle with multiple sclerosis since she was diagnosed in 2021 while filming Dead To Me.
Applegate co-hosts the podcast MeSsy with The Sopranos actress Jamie-Lynn Sigler, who was diagnosed with MS when she was 20 years old. Sigler announced they were taking a “few-week hiatus” on March 31 in a 14-second update for listeners, claiming she and Applegate were going to be focused on their book launches. Applegate had recently released her memoir You With The Sad Eyes, while Sigler’s memoir And So It Is…: A Memoir of Acceptance and Hope is set to publish May 5.
Sigler did not say when the podcast will resume with new episodes, simply sharing, “We will be back in a few weeks.”

Applegate opened up about her experience with MS in a recent essay in The Guardian, detailing the “exhaustion,” the infusions, the difficulty of walking across the room and more.
“With the cancer, it was taken out of my body, and I was able to move on. But MS is my constant companion,” she wrote. “In fact, I will probably go away because of it. It scares me to death. I don’t want to dance with this pain any more, and I don’t want to be in the predicament I’m in. Everything about it sucks.”
The actress also shared she is “prone to infection” because the infusions she receives kill her B cells, which are meant to make antibodies, and sometimes has to “rush to the emergency room.”
Applegate last posted on social media April 2 after her memoir became a New York Times #1 audio bestseller.
“Thank you for making You with the Sad Eyes March’s #1 New York Times audiobook bestseller,” she wrote. “I can’t describe how much this means to me. It was important to me to read the audiobook myself and I’m so appreciative of everyone who has listened to my story.”